@article{Kolosovych_Hanol_2022, title={EVALUATION OF THE EFFICIENCY OF NASOGASTRAL NUTRITION IN PATIENTS WITH SEVERE ACUTE PANCREATITIS}, volume={18}, url={https://msu-journal.com/index.php/journal/article/view/363}, DOI={10.32345/2664-4738.2.2022.02}, abstractNote={<p><strong>Relevance.</strong> Early onset of enteral nutrition (up to 48 hours after hospitalization) in patients with severe acute pancreatitis is associated with a 24% reduction in infectious complications and a 32% reduction in mortality. Data on the possibility of nasogastric tube feeding remain contradictory.</p> <p><strong>Objective:</strong> comparison of the effectiveness and safety of nasogastric administration of food mixtures in patients with severe acute pancreatitis.</p> <p><strong>Methods. </strong>The study included 103 patients with severe acute pancreatitis, which were divided depending on the characteristics of the chosen treatment tactics into three groups: based group (nasogastric nutrition was performed) - 34 patients, comparison group #1 (standard enteral nutrition) - 33 patients and comparison group #2 (parenteral nutrition) - 36 patients. To analyze the effectiveness of nutritional support in the study groups after 7 and 14 days from the beginning of treatment, the level of laboratory parameters was assessed, the incidence of local complications, mortality, duration of multiorgan failure and hospital stay were analyzed.</p> <p><strong>Results. </strong>After 7 and 14 days of nutritional support, a significant difference was found between total protein, albumin, creatinine, urea, cholesterol, glucose and serum Na + (p&lt;0.05) between patients in the main group and comparison group #2, with the level of cholesterol, K + and Na + corresponded to the norm in both groups. There was also a significant difference in the incidence of infected local complications of severe acute pancreatitis in the main group and comparison group #2 - 35.3% and 61.1%, respectively (χ2=4.59, 95% CI 2.43-45.53, p=0.03), duration of multiorgan failure - 12.2±1.7 [8-16] days and 15.3±1.1 [13-18] days, respectively (p&lt;0.001), duration of hospital stay - 55.5±30.5 [27-124] days and 71.5±35.9 [35-148] days, respectively (p=0.04) and fatalities - 14.7% and 36.1%, respectively (χ2=4.13, 95 % CI 0.81-39.68, p=0.04). When comparing these indicators between the main group and the comparison group #1 no significant difference was obtained (p&gt;0.05).</p> <p><strong>Conclusions. </strong>Nasogastric nutrition is an effective and safe method of administration of mixtures in patients with severe acute pancreatitis and can be considered as an alternative to enteral nutrition.</p&gt;}, number={2}, journal={Medical Science of Ukraine (MSU)}, author={Kolosovych, I.V. and Hanol , I.V.}, year={2022}, month={Jun.}, pages={10-16} }