ETHNO-BOTANICAL SURVEY OF PLANTS USED IN A RHEUMATOID ARTHRITIS TREATMENT: A CASE STUDY OF JOS IN NIGERIA

Keywords

Rheumatoid arthritis (RA), Ethno-medicine, Treatment, Medicinal Plants, Jos

Abstract views: 79

How to Cite

Tongshuwar , G., Ojetunde , A., Oyegoke , A., & Oyegoke , T. (2020). ETHNO-BOTANICAL SURVEY OF PLANTS USED IN A RHEUMATOID ARTHRITIS TREATMENT: A CASE STUDY OF JOS IN NIGERIA. Medical Science of Ukraine (MSU), 16(4). https://doi.org/10.32345/2664-4738.4.2020.6

Abstract

Relevance. Rheumatoid arthritis (RA) is an autoimmune disorder leading to the inflammation of the joints. This inflammation finds expression in the lining of the synovial tissues causing swellings and severe pains and deterioration of the bone in the long run. This disease's exact etiology is not yet to be ascertained; however, there are claims of the interplay of genetic and environmental factors. RA is one of the diseases ravaging the people of Jos in Nigeria, owing to the high cost of orthodox medicine.

Objective. The study was carried out to collect information and find out plants used to treat rheumatoid arthritis in Jos, Nigeria, in addition to the availability of the plant(s).

Materials and methods. An electronic-based questionnaire was used to get information from the respondents.

Result. Eight species of plants were reported to be used. Garlic (Allium sativum), Ginger (Zingiber officinale), Turmeric (Curcuma longa), and Onion (Allium cepa) were the dominant plants reportedly used. The parts of plants used are the plant bulb and stem. They are reported to be prepared by grinding and herbal mixture; chewing and decoction were not popular. Respondents with this information reported their willingness to share with both family and friends.

Conclusion. This study shows the availability of traditional RA treatment and the preservation of verbal form knowledge.

https://doi.org/10.32345/2664-4738.4.2020.6

References

1. Hajja G., Aziz B. Medicinal plants in the prevention and treatment of Rheumatoid arthritis. MOJ Bioequivalence & Bioavailability. 2018. DOI:10.15406/MOJBB.2018.05.00084
2. Liao K.P., Alfredsson L., Karlson E.W. Environmental influences on risk of rheumatoid arthritis. Curr Opin Rheumatol. 2009; 21(3):279-83. DOI: https://dx.doi.org/10.1097%2FBOR.0b013e32832a2e16
3. Emery P. Treatment of rheumatoid arthritis. BMJ. 2006 Jan 21; 332(7534):152-5. DOI: https://dx.doi.org/10.1136%2Fbmj.332.7534.152
4. Erhenhi A.H. Medicinal Plants Used for the Treatment of Rheumatism
by Amador People of Edo State, Nigeria. International Journal of Plant Research. 2016; 6(1):7-12. DOI: 10.5923/j.plant.20160601.02
5. Tripathy S., Pradhan D., Anjana M. Anti-inflammatory and anti-arthritic potential of Ammania baccifera Linn. Int J. Pharm Bio Sci. 2010; 1(3):1-7. URL: https://www.researchgate.net/publication/286569799_Anti-inflammatory_and_antiarthritic_potential_of_ammania_baccifera_linn
6. Zewdie K.T. Anethnobotanical study of medicinal plants and biodiversity of trees and shrubs in Jeldu Wereda, Western Shoa Zone, Ethiopia. 2009 July. DOI: 10.13140/RG.2.2.30430.84806. URL: https://www.researchgate.net/publication/307569506_An_ethnobotanical_study_of_medicinal_plants_and_biodiversity_of_trees_and_shrubs_in_Jeldu_Wereda_Western_Shoa_Zone_Ethiopia
7. Ogbole O., Gbolade A., Ajaiyeoba E.O. Ethnobotanical survey of plants used in the treatment of inflammatory disease in the Ogun State of Nigeria. European Journal of Scientific Research. 2010; 43(2):183-91. URL: https://www.researchgate.net/publication/288417018_Ethnobotanical_survey_of_plants_used_in_treatment_of_inflammatory_diseases_in_Ogun_State_of_Nigeria
8. Denisov L.N., Andrianova I.V., Timofeeva S.S. [Garlic effectiveness in rheumatoid arthritis]. Ter Arkh. 1999; 71(8):55-8. [in Russian]. PMID: 10515039. URL: https://pubmed.ncbi.nlm.nih.gov/10515039/
9. Singh H., Krishna G., Baske P.K. Plants used in treatment of joints diseases (rheumatism, arthritis, gout and lumbago) in Mayurbhanj district of Odisha, India. Rep Opin. 2010 January; 2(9):22-6. URL: https://www.researchgate.net/publication/313001859_Plants_used_in_the_treatment_of_joint_diseases_rheumatism_arthritis_gout_and_lumbago_in_Mayurbhanj_district_of_Odisha_India
10. Tyagi D.K., Kumar S., Joshi N. Role of different juices in the management of osteoarthritis, rheumatoid arthritis and backache  a review. J. Ayurveda integr Med Sci. 2017; 2(1):162-6. URL: https://www.jaims.in/index.php/jaims/article/view/174
11. Arreola R., Quintero-Fabián S., López-Roa R.I. Immunomodulation and anti-inflammatory effects of garlic compounds. J. Immunol Res. 2015; Article ID: 401630. DOI: https://doi.org/10.1155/2015/401630
12. Mikali P., Shayegh J., Asghari M.H. Review on the indigenous use and ethnopharmacology of hot and cold natures of phytomedicines in the Iranian traditional medicine. Asian Pac J Trop Mes. 2012; 2:s1189-93. DOI: https://doi.org/10.1016/S2221-1691%2812%2960382-7
13. Flynn D.L., Rafferty M.F., Boctor A.M. Inhibition of human neutrophil-5 lipoxygenase activity by gingerdione,shogaol, capsaicin and related pungent compounds. Prostaglandins Leukotrienes and Medicine. 1986 Oct; 24(2-3):195-8. DOI: https://doi.org/10.1016/0262-1746(86)90126-5
14. Young H.Y., Luo Y.L., Cheng H.Y., Hsieh W.C., Liao J.C., Peng W.H. Analgesic and anti-inflammatory activities of [6]-gingerol. Journal of Ethnopharmacology. 2005 Jan 4; 96(1-2):207-10. DOI: https://doi.org/10.1016/j.jep.2004.09.009
15. Sharma J.N., Srivastava K.C., Gan E.K. Suppressive effects of eugenol and ginger oil on arthritic rats. Pharmacology. 1994 Nov; 49(5):314-8. DOI: https://doi.org/10.1159/000139248
16. vanBreemen R.B., Tao Y., Li W. Cyclooxygenase-2inhibitors in ginger (Zingiberofficinale). Fitoterapia. 2011 Jan; 82(1):38-43. DOI: https://www.researchgate.net/deref/http%3A%2F%2Fdx.doi.org%2F10.1016%2Fj.fitote.2010.09.004
17. Phan P.V., Sohrabi A., Polotsky A., Hungerford D.S., Lindmark L., Frondoza C.G. Ginger extract components suppress induction of chemokine expression in human synoviocytes. Journal of Alternative and Complementary Medicine. 2005 Feb; 11(1):149-54. DOI: https://doi.org/10.1089/acm.2005.11.149
18. Haghighi M., Khalvat A., Toliat T., Jallaei S. Comparing the effects of ginger (Zingiber officinale) extract and ibuprofenon patients with osteoarthritis. Archives of Iranian Medicine. 2005 Aug; 8(4):267-71. URL: https://www.researchgate.net/publication/235007127_Comparing_the_Effects_of_ginger_Zingiber_officinale_extract_and_ibuprofen_On_patients_with_osteoarthritis
19. Jackson J.K., Higo T., Hunter W.L., Burt H.M. The antioxidants curcumin and quercetin inhibit inflammatory processes associated with arthritis. Inflam Res. 2006 Apr; 55(4):168-75. DOI: https://doi.org/10.1007/s00011-006-0067-z
20. Choudhary M., Kumar V., Malhotra H., Singh S. Medicinal plants with potential anti-arthritic activity. Journal of Intercultural Ethnopharmacology. 2015 Apr-Jun; 4(2):147-79. DOI: https://dx.doi.org/10.5455%2Fjice.20150313021918
21. Xu H.X., Mughal S., Taiwo O., Lee S.F. Isolation and characterization of an antibacterial biflavonoid from an African chewing stick Garcinia kola Heckel (Clusiaceae). J Ethnopharmacol. 2013 May 20; 147(2): 497-502. DOI: https://doi.org/10.1016/j.jep.2013.03.047
22. Antia B.S., Pansanit A., Ekpa O.D., Ekpe U.J., Mahidol C., Kittakoop P. Alpha-glucosidase inhibitory, aromatase inhibitory and antiplasmodial activities of a biflavonoid GB1 from Garcinia kola stem bark. Planta Med. 2010 Feb; 76(3):276-77. DOI: https://doi.org/10.1055/s-0029-1186081
23. Seanego C.T., Ndip R.N. Identification and antibacterial evaluation of bioactive compounds from Garcinia kola (Heckel) seeds. Molecules. 2012 May 31; 17(6):6569-84. DOI: https://doi.org/10.3390/molecules17066569
24. Adaramoye O.A., Farombi E.O., Adeyemi E.O., Emerole G.O. Inhibition of human low density lipoprotein oxidation by flavonoids of Garcinia kola seeds. Pak J Med Sci. 2005; 21(3):331-9.
25. Onasanwo S.A., Rotu R.A. Antinociceptive and anti-inflammatory potentials of kolaviron: Mechanisms of action. J. Basic Clin. Physiol. Pharmacol. 2016; 27(4):363-70. DOI: https://doi.org/10.1515/jbcpp-2015-0075
26. Ibironke G.F., Fasanmade A.A. Analgesic and central nervous system depressant activities of kolaviron. (AGarcina kola biflavonoid complex). Afr. J. Biomed. Res. 2015; 18(3):217-23. URL: https://www.ajol.info/index.php/ajbr/article/view/126140
27. Patel D., Kaur G., Sawant M.G., Deshmukh P. Herbal medicine – A natural cure to arthritis. Indian journal of natural products and resources. 2013; 4(1):27-35. URL: https://www.researchgate.net/publication/274076263_Herbal_Medicine_-_A_natural_cure_to_arthritis
Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.